Treatment of resistant giant cell arteritis with etanercept.
نویسنده
چکیده
منابع مشابه
Histopathologic Features of Giant Cell Arteritis in an Actinic Granuloma Lesion
The association between actinic granuloma and giant cell arteritis (temporal arteritis) has been claimed by some authors. There is a hypothesis that actinic radiation has the principal role in the etiology of both diseases in a similar way. Here, we report a case of actinic granuloma that had characteristic pathologic features of giant cell arteritis in histopathologic examination without clini...
متن کاملA double-blind placebo controlled trial of etanercept in patients with giant cell arteritis and corticosteroid side effects.
OBJECTIVE Open label studies have suggested that tumour necrosis factor (TNF) antagonists led to sustained improvement and corticosteroid sparing effect in patients with giant cell arteritis (GCA). To confirm these observations, we conducted a randomised, double-blind, placebo controlled trial with etanercept in patients with biopsy-proven GCA with side effects secondary to corticosteroids. M...
متن کاملLong-term efficacy and safety of tocilizumab in giant cell arteritis and large vessel vasculitis
Giant cell arteritis (GCA) is a chronic systemic vasculitis affecting large-sized and medium-sized vessels. Glucocorticoids are currently the mainstay of treatment for GCA and associated large vessel vasculitis (LVV) but are associated with frequent adverse events. Methotrexate has only demonstrated a modest benefit while anti-TNF biological agents (infliximab and etanercept) have been ineffica...
متن کاملFenofibrate and losartan.
Tan et al recently described a case of ''resistant giant cell arteritis'' successfully treated with etanercept. 1 Their patient, who had classical symptoms of polymyalgia rheu-matica (PMR), developed headaches while receiving low dose steroids. Biopsy of a temporal artery showed no arteritis. Because giant cell arteritis (GCA) was suspected on clinical grounds, high dose steroids were institute...
متن کاملThe utility of tumour necrosis factor blockade in orphan diseases.
A variety of rheumatic disorders have been successfully treated with tumour necrosis factor (TNF) blockers. However, TNF blockade may be useful in a number of rare diseases. Preliminary data suggest that several forms of vasculitis appear responsive to TNF antagonists-Behcet's disease, Churg-Strauss vasculitis, polyarteritis nodosa, and giant cell arteritis, among others. Wegener's granulomatos...
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 63 4 شماره
صفحات -
تاریخ انتشار 2004